MOTS-c

Longevity & Cellular · 10 mg fill · Research Peptide

A 16-amino-acid peptide encoded inside the mitochondrial 12S rRNA gene.

Overview

MOTS-c is a mitochondrial-derived peptide: a 16-amino-acid sequence encoded within the mitochondrial 12S rRNA gene (MT-RNR1), first described in 2015. It is one of a small set of peptides transcribed from mitochondrial rather than nuclear DNA, and the published mechanism of interest is activation of AMP-activated protein kinase (AMPK) via the folate–AICAR pathway. Work to date is preclinical. Supplied lyophilized for laboratory research.

Specifications

Form

Lyophilized powder

Vial size

10 mg

Class

Mitochondrial-derived peptide (MDP)

Encoded by

Mitochondrial 12S rRNA gene (MT-RNR1)

Residues

16 amino acids

Pathway studied

AMPK activation via folate–AICAR

Purity

Stated on the batch COA

Reconstitution

Bacteriostatic water

Storage

Lyophilized: room temperature, protected from light

Documentation

Batch-specific COA on request

Research use

• AMPK signalling research
• Mitochondrial-derived peptide biology
• Cellular metabolic-homeostasis models
• Comparative mitochondrial-encoded peptide studies

For research use only. This product is intended for laboratory and educational research purposes only. It is not made, labelled or sold as a drug, supplement or medical device, and it is not for human or veterinary consumption, diagnosis, treatment or cure of any condition.

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